Kutshanje, izigebenga ezibini zecuba, i-PMI kunye ne-BAT, zipapashe amaphepha ophando kwiijenali zezonyango eziphambili zamazwe ngamazwe.Iziphumo zophando zibonisa ukuba iimveliso ezintsha zecuba ezifana ne-e-cigarettes kunye nokushisa-ukungatshisi aziyingozi kwaye zinetyhefu kune-cigarettes yendabuko, kwaye inokunciphisa kakhulu impembelelo kwinkqubo yokuphefumula.umonakalo.
Njengoko ulwazi lwabantu malunga neengozi zokutshaya lukhula, i-e-cigarettes iya iqondwa ngakumbi luluntu njengento ethatha indawo yecuba.Nangona kunjalo, ifuthe lexesha elide le-flavoredi-e-cigaretteimixube yencasa kunye nomsi wecuba kubantu abatshayayo kusaza kuphononongwa ngakumbi.
Kungekudala, u-PMI uPhilip Morris International upapashe ingxelo yophando "Uvavanyo lwe-inhalation toxicity yomsi wecuba kunye ne-aerosols evela kumxube we-flavour: isifundo se-5-iveki kwi-A / J iigundane" kwiBritish Journal ye-Toxicology "I-Journal ye-Applied Toxicolog", ichaza iinkcukacha. yezihloko ezinxulumene Amanyathelo ophando kunye neziphumo.
Kuvavanyo, iimpuku ezingamadoda angama-87 kunye ne-174 eyi-nulliparous kunye neempuku ezikhulelweyo zabelwa ngokungacwangciswanga kumaqela ovavanyo ayi-9, kwaye zaqhutywa emoyeni, umsi wecuba, kunye ne-e-cigarette aerosols ezinemigxinano emithathu eyahlukeneyo yencasa, ephezulu, ephakathi, kwaye ephantsi.Ukuvezwa ukuya kuthi ga kwiiyure ezi-6 ngosuku, iintsuku ezi-5 ngeveki, kwiiveki ezi-5 kulandelwa yi-necropsy, ubunzima bomzimba kunye novavanyo lwe-histopathological.
Umfanekiso ubonisa idatha yovavanyo lokudumba kwemiphunga yempuku.Ingabonwa ukuba idatha echaphazelekayo yeegundane ezivezwe kumsi wecuba zinempendulo ecacileyo (inxalenye ebomvu)
Iziphumo zokugqibela zovavanyo zibonise ukuba xa iigundane zibonakaliswe kwi-e-cigarette aerosols kunye nangaphandle kwe-flavour, xa kuthelekiswa nezo zibonakaliswe kumsi wecuba, akukho tshintsho lubalulekileyo kwizitho zokuphefumula, impumlo, kunye nezicubu ze-epithelial ze-laryngeal, ezibonisa ukuba i-e-cigarettes. I-sol ayicaphuki kancinci kwizicubu ezihambelanayo kunye namalungu.Iziphumo zovavanyo zingqina ukuba, xa kuthelekiswa nemidiza yesintu,i-e-cigaretteskunokunciphisa kakhulu ukuvuvukala kwemiphunga, kunye nomonakalo kwimpumlo, umqala kunye ne-tracheal epithelium.
I-BAT yaseBritani yaseMelika iTobacco yapapasha iphepha lophando elinesihloko esithi "Uvavanyo loVavanyo kunye neNdlela ye-Vitro yokuya kwiBridge phakathi kweentlobo ezahlukeneyo zeemveliso zecuba ezivuthayo" kwi "Igalelo kwiCuba kunye noPhando lweNicotine" kwijenali yesayensi, kwaye yenza uphando kwi-THP (imveliso ye-HNB) I-Toxicology uvavanyo.
Kuvavanyo, ii-aerosols kunye nomsi wecuba ohlukeneyo ezintlanu ze-THP kunye ne-THP enye esisiseko zasetyenziswa njengendawo yovavanyo, kwaye i-cytotoxicity yavavanywa ngokusebenza kweeseli ze-epithelial zemiphunga yomntu.Iziphumo zibonise ukuba zonke iimpendulo ze-cytotoxic kwiqela le-THP bezimalunga nama-95% ngaphantsi kunezo zeqela lomsi wecuba, kwaye akukho mahluko ubalulekileyo kwityhefu phakathi kwe-THP ezintlanu ezahlukeneyo kunye ne-THP esisiseko.
Ngokutsho kophononongo, uphuhliso kunye nonikezelo lwezinye icuba kunye neemveliso inikotini zikhula ngokukhawuleza, abathengi baya besamkela ngakumbi iimveliso ezintsha ezifana ne-THP, kwaye ukhuseleko kunye nobungozi bayo njengenxalenye yovavanyo lwe-toxicological lufanelekile ingqalelo kushishino.Kuphela xa imveliso ihlangabezana nemigangatho (kubandakanywa nokusebenza kwebhetri) inokudlala ngcono indima yayo njengesicwangciso sempilo yoluntu.
Iimbekiselo
Ee Tsin Wong, Karsta Luettich, Lydia Cammack, et al.Uvavanyo lwetyhefu yokuphefumla yomsi wecuba kunye ne-aerosols evela kwimixube yencasa: Uphononongo lweeveki ezi-5 kwiimpuku ze-A/J.Ijenali ye-toxicology esetyenzisiweyo, ngo-2022
Tomasz Jaunky, David Thorne, Andrew Baxter, et al.Indlela yoVavanyo yoVavanyo kunye ne-In Vitro yokuya kwibhulorho phakathi kweentlobo ezahlukeneyo zeemveliso zecuba ezishushu.Igalelo kuPhando lweCuba kunye neNicotine, ngo-2022
Ixesha lokuposa: Dec-16-2022
